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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Cognitive profile in young adults born preterm at very low birthweight
Gro C C Løhaugen1, Arne Gramstad, Kari Anne I Evensen
1Department of Paediatrics and Rehabilitation, Sørlandet Hospital, Arendal, Norway. gro.c.lohaugen@ntnu.no
Insights
Very low birthweight (VLBW) individuals show lasting cognitive deficits, with over half scoring low on IQ tests. Comprehensive cognitive assessment is crucial for VLBW young adults to ensure appropriate support for academic and career success.
Area of Science:
- Neuroscience
- Developmental Pediatrics
- Cognitive Psychology
Background:
- Very low birthweight (VLBW; ≤ 1500g) can impact long-term neurodevelopment.
- Cognitive outcomes in young adulthood for VLBW individuals require comprehensive evaluation.
Purpose of the Study:
- To assess general cognitive ability at age 19 in individuals born with very low birthweight (VLBW) compared to term-born controls.
- To identify specific cognitive domains affected by VLBW.
Main Methods:
- A hospital-based follow-up study included 55 VLBW participants and 81 term-born comparison individuals.
- Cognitive function was assessed using the Wechsler Adult Intelligence Scale III (WAIS-III) to measure general cognitive ability.
Main Results:
- Over half (53%) of VLBW participants achieved low IQ scores, significantly more than controls (OR 6.4).
- VLBW individuals scored lower across full-scale, verbal, and performance IQ measures, and all four WAIS-III indices.
- Arithmetic and visual-perceptual tasks were particularly challenging for the VLBW group.
Conclusions:
- Very low birthweight has a global and persistent impact on cognitive ability into young adulthood.
- Full-scale IQ assessment is vital for identifying learning difficulties in VLBW young adults.
- Early identification and support are recommended to enhance academic achievement and future employment opportunities for VLBW individuals.
Aim:
the aim of this study was to assess cognitive function at the age of 19 years in individuals of very low birthweight (VLBW; ≤ 1500g) and in term-born comparison individuals.
Method:
in this hospital-based follow-up study, 55 VLBW participants (30 males, 25 females; mean birthweight 1217g, SD 233g; mean gestational age 29.1wks, SD 2.5wks) and 81 comparison individuals (42 males, 39 females; mean birthweight 3707g, SD 433g; mean gestational age 39.7wks, SD 1.2wks) were examined with a standardized IQ test (Wechsler Adult Intelligence Scale III) to assess general cognitive ability.
Results:
over half (53%) of the VLBW participants achieved a low IQ score (defined as >1SD below the mean in the comparison group; odds ratio 6.4 vs comparison individuals; 95% confidence interval 2.8-14.4; p<0.001). None of the VLBW group, compared with 22% of the comparison individuals, achieved a high IQ score (>1SD above the comparison mean). VLBW participants scored lower than comparison individuals on full, verbal, and performance IQ, as well as on all four indices (p ≤0.001). The subtest profile indicated problems on all subtests, but especially on those related to arithmetic and visual-perceptual tasks.
Interpretations:
few studies have undertaken a comprehensive assessment of general cognitive outcome (IQ) among young adults of VLBW. Our results indicate that VLBW seems to have a global and lasting impact on cognitive ability. Full-scale IQ assessment may reveal important learning problems in young adults of VLBW, and should be performed to inform appropriate assistance to enhance academic achievement and the chances of permanent employment as adults.
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