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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Characteristics and Functions of Blood01:26

Characteristics and Functions of Blood

Blood is specialized connective tissue comprising about 8% of the body mass. It has a thick, liquid extracellular matrix that contains cells, dissolved proteins, and electrolytes, making it five times more viscous than water. Blood is warm, around 38°C, and has an alkaline pH ranging from 7.35 to 7.45.
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...
Blood Flow01:29

Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Composition of Blood01:22

Composition of Blood

The blood in our bodies comprises three major components: blood plasma, formed elements, and the extracellular matrix. Blood plasma is a yellowish fluid that constitutes 55% of the total blood volume. It is primarily made up of water and essential substances such as electrolytes and proteins. Blood plasma serves as a medium for transporting blood cells and also contains nutrients, enzymes, hormones, antibodies, and gases.
Formed elements constitute the remaining 45% of the blood volume. These...

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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

How much blood is needed?

E Seifried1, H Klueter, C Weidmann

  • 1Institute for Transfusion Medicine and Immunohaematology, German Red Cross Blood Donor Service Baden-Wuerttemberg-Hessen and Clinics of the Johann Wolfgang Goethe University Frankfurt/Main, Frankfurt/Main, Germany. e.seifried@blutspende.de

Vox Sanguinis
|December 24, 2010
PubMed
Summary
This summary is machine-generated.

Developed countries face a growing demand for blood components due to aging populations, alongside a declining blood donation rate. Novel strategies are needed to manage the blood supply chain effectively.

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Repetitive Blood Sampling from the Subclavian Vein of Conscious Rat
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Repetitive Blood Sampling from the Subclavian Vein of Conscious Rat
04:52

Repetitive Blood Sampling from the Subclavian Vein of Conscious Rat

Published on: February 9, 2022

Area of Science:

  • Transfusion Medicine
  • Geriatric Medicine
  • Public Health

Background:

  • Aging populations in developed countries are increasing the need for standard blood components.
  • Complex medical procedures, including transplantation and surgery, are increasingly performed on older patients.
  • Societal shifts and attitudes towards altruistic behavior may decrease regular blood donations.

Purpose of the Study:

  • To analyze the dual trends of increasing blood component consumption and decreasing blood donation rates.
  • To highlight the challenges posed by demographic changes to blood supply chains.
  • To emphasize the need for innovative solutions in blood management.

Main Methods:

  • Analysis of demographic trends and their impact on healthcare demands.
  • Review of factors influencing blood donation behavior.
  • Assessment of current and future blood substitute technologies.

Main Results:

  • Blood component consumption is rising due to an aging population and advanced medical interventions.
  • Regular blood donations are projected to decline in developed countries.
  • Current blood substitute technologies are not yet viable alternatives for widespread use.

Conclusions:

  • A significant gap between blood supply and demand is anticipated.
  • Proactive strategies are essential to address declining blood donations and increasing consumption.
  • Re-engaging inactive donors and optimizing blood component utilization are critical steps.