Related Experiment Video
Updated: Jun 5, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Transfusion practice and safety: current status and possibilities for improvement
M F Murphy1, S J Stanworth, M Yazer
1NHS Blood & Transplant, John Radcliffe Hospital, Oxford OX3 9BQ, UK. mike.murphy@nhsbt.nhs.uk
Poor hospital transfusion practices are common and lead to severe patient harm. Enhancing transfusion safety requires understanding errors, simplifying procedures with technology, setting standards, improving hospital organization, and further research.
Area of Science:
- Medical Science
- Patient Safety
- Healthcare Management
Background:
- Audits and incident reporting reveal frequent poor hospital transfusion practices.
- These practices can lead to severe patient consequences, highlighting critical safety gaps.
Purpose of the Study:
- To identify key areas for improving hospital transfusion practices.
- To emphasize the need for a comprehensive approach to enhance patient safety in transfusion medicine.
Main Methods:
- Analysis of audit data and incident reports from national haemovigilance schemes.
- Review of existing hospital transfusion processes and identification of error-prone areas.
Main Results:
- Poor transfusion practices are prevalent, indicating systemic issues within hospitals.
- Catastrophic patient outcomes are occasionally linked to these suboptimal practices.
Conclusions:
- Improving hospital transfusion safety necessitates a multi-faceted strategy.
- This includes error analysis, technological integration, performance monitoring, organizational improvements, staff training, and research into blood use and alternatives.
Related Concept Videos
Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Kidney Transplant I: Introduction
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Blood Typing
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...