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Related Experiment Video

Updated: Jun 5, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Haemovigilance: an effective tool for improving transfusion practice.

R R P de Vries¹, J-C Faber, P F W Strengers

¹Department of Immunohematology and Bloodtransfusion, Leiden University Medical Center, Leiden, The Netherlands. rrpdevries@lumc.nl

|December 24, 2010

Summary

Haemovigilance systems demonstrate blood transfusions are safe, with most adverse events occurring in hospitals due to errors. These systems improve transfusion safety and can monitor other medical products.

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Last Updated: Jun 5, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Area of Science:

Transfusion Medicine
Patient Safety
Public Health

Background:

Haemovigilance is a critical system for monitoring blood transfusion safety.
This review examines the evolution and future of haemovigilance in transfusion medicine.

Observation:

Blood transfusion is relatively safe compared to pharmaceuticals, with high safety standards in Europe.
Most serious adverse reactions and preventable errors in blood transfusions occur within hospitals.
Certain adverse reactions, like anaphylaxis, are inherent risks of transfusion.

Findings:

Effective haemovigilance systems identify safety improvements and validate implemented measures.
Organizational structure of haemovigilance systems varies, but outcomes can be similar.
International collaboration significantly enhances haemovigilance efforts.

Implications:

Haemovigilance can extend to monitoring alternatives like cell savers and other human products (cells, tissues, organs).
These systems can improve non-safety aspects of blood transfusion, such as appropriate use.
The principles of haemovigilance are applicable to a broader range of medical treatments involving biological products.