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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

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Benign acral lesions showing parallel ridge pattern on dermoscopy.

¹Department of Dermatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. mtanioka@kuhp.kyoto-u.ac.jp

The Journal of Dermatology

|December 24, 2010

Summary

The parallel ridge pattern (PRP) on dermoscopy is highly specific for acral melanoma. However, some benign lesions also exhibit PRP, necessitating careful evaluation to differentiate them from malignancy.

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Area of Science:

Dermatology
Dermoscopy
Oncology

Background:

The parallel ridge pattern (PRP) is a key dermoscopic feature with high specificity for acral melanoma.
Distinguishing benign lesions with PRP from melanoma is crucial for accurate diagnosis.

Purpose of the Study:

To review benign acral lesions that exhibit the parallel ridge pattern (PRP) on dermoscopy.
To highlight features that differentiate these benign lesions from malignant melanoma.

Main Methods:

Literature review of dermoscopic images and clinical data of acral lesions.
Analysis of diagnostic criteria for differentiating benign PRP lesions from melanoma.

Main Results:

Several benign acral lesions, including dye-induced pigmentation, Peutz-Jeghers syndrome macules, drug-induced hyperpigmentation, subcorneal hemorrhage, and pigmented warts, can mimic the PRP of melanoma.
Clinical history and associated symptoms are vital for distinguishing benign from malignant lesions.

Conclusions:

While PRP is a strong indicator of acral melanoma, its presence in benign lesions poses a diagnostic challenge.
Dermatologists must consider clinical context and, when in doubt, recommend skin biopsy to exclude melanoma.