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Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution

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Avène Thermal Spring Water: an active component with specific properties.

C Merial-Kieny¹, N Castex-Rizzi, B Selas

¹Laboratoires dermatologiques Avène, Lavaur, France. christelle.merial.kieny@pierre-fabre.com

Journal of the European Academy of Dermatology and Venereology : JEADV

|December 24, 2010

Summary

Avène Thermal Spring Water (TSW), with low mineral content, shows anti-inflammatory and skin-healing properties. Clinical studies confirm its effectiveness for chronic skin conditions and post-procedure recovery.

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Area of Science:

Dermatology
Biochemistry

Background:

Avène Thermal Spring Water (TSW) possesses a unique low mineral composition.
Its biological effects are attributed to its natural properties.

Purpose of the Study:

To investigate the multifaceted effects of Avène TSW.
To validate its therapeutic potential in dermatological conditions.

Main Methods:

In vitro studies assessed effects on membrane fluidity, antiradical activity, and immune mediators.
Clinical evaluations were conducted at a hydrotherapy center and in post-dermatological procedure settings.

Main Results:

Avène TSW demonstrated significant antiradical and anti-inflammatory actions in vitro.
It stimulated keratinocyte differentiation and modulated immune response mediators.
Clinical trials showed efficacy in treating atopic dermatitis and aiding recovery from procedures like photodynamic therapy.

Conclusions:

Avène TSW is a scientifically validated active component for dermatological applications.
Its unique properties support its use in managing chronic skin diseases and enhancing post-procedural healing.