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Related Concept Videos

Histology of the Uterus01:19

Histology of the Uterus

The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
The endometrium is the...
Proliferative Phase01:20

Proliferative Phase

The proliferative phase typically occurs after menstruation and lasts between 6 to 13 days in a standard 28-day cycle. This phase involves the reconstruction of the endometrium, guided by estrogen produced by the developing ovarian follicle.
Notably, the stratum basale, the basal layer of the endometrium, including the basal parts of the uterine glands, remains unaffected by menstruation. Stem cells in this layer undergo mitosis, regenerating the stratum functionalis and thickening the...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Uterine Tubes01:16

Uterine Tubes

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
Mitral Stenosis II: Clinical features and Diagnostic Tests01:23

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...

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Related Experiment Video

Updated: Jun 5, 2026

Non-Invasive Ultrasound Assessment of Endometrial Cancer Progression in Pax8-Directed Deletion of the Tumor Suppressors Arid1a and Pten in Mice
07:44

Non-Invasive Ultrasound Assessment of Endometrial Cancer Progression in Pax8-Directed Deletion of the Tumor Suppressors Arid1a and Pten in Mice

Published on: February 17, 2023

Asymptomatic endometrial thickening.

Wendy Wolfman, Nicholas Leyland, Mark Heywood

    Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'Obstetrique Et Gynecologie Du Canada : JOGC
    |December 24, 2010
    PubMed
    Summary
    This summary is machine-generated.

    This guideline provides recommendations for managing asymptomatic endometrial thickening in postmenopausal women, aiming to reduce unnecessary procedures and patient anxiety. Appropriate management ensures women with endometrial polyps are handled correctly.

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    Establishing a Mouse Model of Thin Endometrium
    05:26

    Establishing a Mouse Model of Thin Endometrium

    Published on: November 1, 2024

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    Last Updated: Jun 5, 2026

    Non-Invasive Ultrasound Assessment of Endometrial Cancer Progression in Pax8-Directed Deletion of the Tumor Suppressors Arid1a and Pten in Mice
    07:44

    Non-Invasive Ultrasound Assessment of Endometrial Cancer Progression in Pax8-Directed Deletion of the Tumor Suppressors Arid1a and Pten in Mice

    Published on: February 17, 2023

    Establishing a Mouse Model of Thin Endometrium
    05:26

    Establishing a Mouse Model of Thin Endometrium

    Published on: November 1, 2024

    Area of Science:

    • Gynecology
    • Radiology
    • Clinical Practice Guidelines

    Background:

    • Asymptomatic endometrial thickening on ultrasound in postmenopausal women requires clear management strategies.
    • Endometrial polyps are a common finding that necessitates appropriate clinical assessment.

    Purpose of the Study:

    • To develop clinical recommendations for assessing endometrial thickening in asymptomatic postmenopausal patients.
    • To ensure appropriate management of asymptomatic endometrial thickening and polyps detected via ultrasound.

    Main Methods:

    • Systematic literature search of EMBASE, Cochrane, and PubMed (1970-2010) for relevant studies.
    • Inclusion of systematic reviews, RCTs, CCTs, and observational studies.
    • Inclusion of grey literature from health technology assessment agencies and clinical trial registries.

    Main Results:

    • Evidence synthesis to inform clinical recommendations.
    • Ranking of recommendations based on the Canadian Task Force on Preventative Health Care criteria.
    • Updated literature search incorporated up to April 2010.

    Conclusions:

    • Adoption of recommendations expected to decrease patient anxiety, pain, and procedural risks.
    • Anticipated reduction in healthcare costs through elimination of unnecessary interventions.
    • Improved patient outcomes for postmenopausal women with asymptomatic endometrial findings.