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Related Concept Videos

Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
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Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Cushing Syndrome II: Pathophysiology01:19

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Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
Sex Linked Disorders01:43

Sex Linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.

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Related Experiment Video

Updated: Jun 5, 2026

Learning Modern Laryngeal Surgery in a Dissection Laboratory
07:30

Learning Modern Laryngeal Surgery in a Dissection Laboratory

Published on: March 18, 2020

[Lynch syndrome: genetics and surgery].

Manuel Ferrer Márquez1, Angel Reina Duarte, Vanesa Maturana Ibáñez

  • 1Hospital Torrecárdenas, Almería, España. manuferrer78@hotmail.com

Cirugia Espanola
|December 24, 2010
PubMed
Summary

Lynch Syndrome, the most common hereditary colorectal cancer, stems from DNA repair gene mutations. Identifying and managing this condition involves clinical, molecular, and surgical strategies for prevention.

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Last Updated: Jun 5, 2026

Learning Modern Laryngeal Surgery in a Dissection Laboratory
07:30

Learning Modern Laryngeal Surgery in a Dissection Laboratory

Published on: March 18, 2020

Area of Science:

  • Genetics
  • Oncology
  • Molecular Biology

Context:

  • Lynch Syndrome is the most prevalent hereditary colorectal cancer.
  • It arises from germline mutations in DNA mismatch repair genes.
  • Diagnosis relies on complex clinical and molecular criteria.

Purpose:

  • To review the genetics of Lynch Syndrome.
  • To outline diagnostic approaches.
  • To discuss surgical management and prevention strategies.

Summary:

  • This review covers the genetic basis of Lynch Syndrome, including mismatch repair gene mutations.
  • It details the challenges and methods for identifying affected individuals.
  • Management strategies encompassing surgical interventions and preventative measures are examined.

Impact:

  • Improved understanding of Lynch Syndrome genetics and diagnosis.
  • Guidance for clinical management and prevention of hereditary colorectal cancer.
  • Facilitates early identification and intervention for at-risk populations.