Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head

Published on: April 12, 2022

Imageless navigation system does not improve component rotational alignment in total knee arthroplasty.

Tao Cheng¹, Guoyou Zhang, Xianlong Zhang

¹Department of Orthopaedic Surgery, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.

The Journal of Surgical Research

|December 24, 2010

Summary

Imageless computer-assisted navigation improves lower limb alignment and component positioning in total knee arthroplasty (TKA). However, it does not enhance rotational alignment, necessitating further research on clinical outcomes.

Related Concept Videos

Knee Joint

Knee Joint

The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris group...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Direct NLRP3 inflammasome inhibitors for cardiovascular therapeutics: a comparative review of synthetic and natural candidates.

Frontiers in pharmacology·2026

Same author

Integrative computational simulations and functional assays decode allosteric dysregulation in a pathogenic SIRT6 variant.

International journal of biological macromolecules·2026

Same author

Mechanistic basis of N-terminal domain-mediated allostery in SIRT6: integrating molecular dynamics simulations and biochemical assays.

Molecular diversity·2025

Same author

Baicalein protects against heart failure by improving mitochondrial dysfunction and regulating endoplasmic reticulum stress to reduce apoptosis in vitro and in vivo.

International journal of immunopathology and pharmacology·2025

Same author

Elevated O<sub>3</sub> has stronger effects than CO<sub>2</sub> on soil nematode abundances but jointly inhibits their diversity in paddy soils.

Journal of environmental management·2024

Same author

Both Short-term and Long-term Ozone Pollution Alters the Chemical Composition of rice Grain.

Bulletin of environmental contamination and toxicology·2024

Area of Science:

Orthopedic Surgery
Medical Imaging
Biomechanical Engineering

Background:

Computer-assisted surgery aims to enhance precision and reduce variability in surgical procedures.
A global discussion persists regarding the utility of computer-assisted navigation in total knee arthroplasty (TKA).
This study compares radiographic outcomes of TKA using imageless computer-assisted navigation versus conventional methods.

Purpose of the Study:

To systematically compare radiographic outcomes of TKA performed with imageless computer-assisted navigation against conventional techniques.
To evaluate the impact of navigation on lower limb axis, component alignment, and rotational accuracy.

Main Methods:

A comprehensive meta-analysis of 29 quasi-randomized/randomized controlled trials and 11 prospective comparative studies.

Related Experiment Videos

Last Updated: Jun 5, 2026

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head

Augmented Reality Navigation-Guided Core Decompression for Osteonecrosis of Femoral Head

Published on: April 12, 2022

Searches conducted across major databases (PubMed, EMBASE, Web of Science, Cochrane) and orthopedic journals.

Subgroup analysis performed to assess heterogeneity related to radiographic methods.

Main Results:

Imageless navigation significantly reduced outliers in lower limb axis (risk ratio 0.54-0.39) and component alignment in coronal and sagittal planes (cut-off 2°-3°).
No significant differences were found in rotational alignment outliers between navigated and conventional TKA groups via CT scans.
Strong statistical heterogeneity was noted in rotational alignment results.

Conclusions:

Imageless computer-assisted navigation enhances lower limb axis and coronal/sagittal component alignment in TKA.
Rotational alignment in TKA is not improved by imageless navigation.
Further multi-center trials with long-term follow-up are required to ascertain clinical and functional benefits.