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[Cognitive rehabilitation in multiple sclerosis: a review of the literature]
H Brissart1, F Daniel, E Morele
1Service de neurologie, hôpital central, CHU de Nancy, avenue du Maréchal-de-Lattre-de-Tassigny, 54035 Nancy cedex, France. h.brissart@chu-nancy.fr
Introduction:
Cognitive impairment is now well-known in multiple sclerosis (MS). However, few rehabilitation interventions are proposed or really efficient.
Objectives:
To present a review of cognitive rehabilitation intervention research conducted in people with multiple sclerosis (MS), regarding different findings about episodic memory, working memory, attention and executive function disorders in MS.
Data Sources:
A search of Medline (yield 20 papers) and of PsychInfo (yield 1 article), using combinations of the following terms: cognitive rehabilitation, multiple sclerosis, cognitive therapy, neuropsychological rehabilitation, in the title or in the abstract, from 1960 to March 2010, excluding animal studies.
Results:
Episodic memory rehabilitation studies appear to be promising. Programs on working memory, attention and executive functions are in the very early phases.
Conclusions:
Results are encouraging and allow specific recommendations for future research about: (1) inclusion criteria, often not defined, (2) a specific baseline adapted to the program of rehabilitation, (3) a control measure regarding program efficiency and (4) a role for the psychologist (presence and advice during the program).

