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Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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MSX1 and TGF-beta3 are novel target genes functionally regulated by FOXE1

Isabella Venza1, Maria Visalli, Luca Parrillo

  • 1Department of Surgical Specialities, University of Messina, Italy.

Human Molecular Genetics
|December 24, 2010
PubMed
Summary

Forkhead box E1 (FOXE1) mutations cause Bamforth-Lazarus syndrome. This study reveals FOXE1 directly regulates MSX1 and TGF-β3, crucial for craniofacial development and cleft palate.

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