Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Internal and external therapy with corticoids].

J Pichl1, H Schell

  • 1Medizinische Klinik I mit Poliklinik, Universität Erlangen-Nürnberg.

Zeitschrift Fur Hautkrankheiten
|June 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The haematoma and its role in bone healing.

Journal of experimental orthopaedics·2017
Same author

Electrochemical degradation of perfluoroalkyl and polyfluoroalkyl substances (PFASs) in groundwater.

Water science and technology : a journal of the International Association on Water Pollution Research·2015
Same author

BMP delivery complements the guiding effect of scaffold architecture without altering bone microstructure in critical-sized long bone defects: A multiscale analysis.

Acta biomaterialia·2015
Same author

Deterioration of fracture healing in the mouse model of NF1 long bone dysplasia.

Bone·2012
Same author

An experimental setup to evaluate innovative therapy options for the enhancement of bone healing using BMP as a benchmark--a pilot study.

European cells & materials·2012
Same author

[Fractures of the radial head and neck].

Zeitschrift fur Orthopadie und Unfallchirurgie·2011
Same journal

[Acne vulgaris: morphologic, endocrinologic and psychosomatic aspects].

Zeitschrift fur Hautkrankheiten·1990
Same journal

[Anti-androgen treatment of hirsutism with cyproterone acetate].

Zeitschrift fur Hautkrankheiten·1990
Same journal

[Changes in sunscreening products in West Germany between 1988 and 1989/90].

Zeitschrift fur Hautkrankheiten·1990
Same journal

[Effect of treatment with salt from the Dead Sea (Tomesa therapy) on epidermal Langerhans cells--a clinical study].

Zeitschrift fur Hautkrankheiten·1990
Same journal

[DNA determination by cytophotometry in bowenoid papules in comparison with condylomata acuminata and Bowen's disease].

Zeitschrift fur Hautkrankheiten·1990
Same journal

[Adverse drug reactions on hair].

Zeitschrift fur Hautkrankheiten·1990
See all related articles

Corticoids offer therapeutic benefits but cannot separate beneficial effects from side effects. Increasing corticoid dosage or potency elevates risks for both topical and systemic applications.

Area of Science:

  • Pharmacology
  • Toxicology
  • Clinical Medicine

Context:

  • Corticoids are widely used for their anti-inflammatory and immunosuppressive properties.
  • Their therapeutic actions are mediated through a unified mechanism of action.
  • Understanding corticoid properties is crucial for safe and effective clinical use.

Purpose:

  • To elucidate the inherent challenges in separating beneficial effects from adverse effects of corticoids.
  • To highlight the dose-dependent relationship between therapeutic activity and side effect risk.
  • To emphasize the potential for systemic side effects even with topical corticoid application.

Summary:

  • The mechanism of action for corticoids makes it impossible to isolate therapeutic benefits from adverse effects.

Related Experiment Videos

  • Both systemic and topical administration of corticoids carry risks, with higher potency and prolonged use increasing these risks.
  • Systemic corticoid use can impact various organs beyond the skin, necessitating careful patient monitoring.

    • Impact:

    • This understanding is vital for optimizing corticoid therapy, balancing efficacy with safety.
    • It informs clinical decision-making regarding appropriate dosing and duration of corticoid treatment.
    • Highlights the need for vigilance regarding potential systemic toxicity, particularly with potent topical formulations.