CT manifestations of schizencephaly

Schizencephaly is a neuronal migration malformation characterized by a cleft traversing the cerebral hemisphere. The cleft is lined by heterotopic gray matter, and the lips of the cleft may be fused or separated. Often associated with anomalies of the septum pellucidum or corpus callosum, and polymicrogyria, schizencephaly has characteristic CT findings. Of 17 patients with this lesion detected by CT 2 had bilateral schizencephaly.