Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perspectives of psychiatrists on Mental Health Care Act, 2017: An in-depth pilot survey.

Industrial psychiatry journal·2025
Same author

Lifestyle modification for mental health and well-being.

Indian journal of psychiatry·2024
Same author

Study of Determinants of Somatoform Disorders in Children.

Cureus·2023
Same author

Management of issues relating to marriage, mental illness, and Indian legislation.

Indian journal of psychiatry·2022
Same author

Trends and issues in community mental health programs in India: The Ranchi Institute of Neuropsychiatry and Allied Sciences experience.

Industrial psychiatry journal·2021
Same author

COVID-19 pandemic hype: Losers and gainers.

Indian journal of psychiatry·2020
Same journal

Marital adjustment, psychological distress, and Internet addiction among married couples in an urban community: A cross-sectional study.

Industrial psychiatry journal·2026
Same journal

Neuropsychiatric presentation of Wernicke-Korsakoff syndrome secondary to chronic alcohol dependence.

Industrial psychiatry journal·2026
Same journal

Theoretical underpinnings of flow and its relation with academic engagement: A narrative review.

Industrial psychiatry journal·2026
Same journal

Association of sleep quality and urinary melatonin levels with endometrial cancer: A case control pilot study.

Industrial psychiatry journal·2026
Same journal

Dengue: A cause for anxiety in endemic regions, a Thai experience.

Industrial psychiatry journal·2026
Same journal

Enhancing well-being and managing depression in alcohol dependence patients through well-being therapy.

Industrial psychiatry journal·2026
See all related articles

Related Experiment Video

Updated: Jun 5, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Intracranial (structural) changes in obsessive- compulsive disorder: A computerized tomography scan study.

Deepak Kumar Giri1, Indira Sharma

  • 1Department of Psychiatry, RINPAS, Kanke, Ranchi, India.

Industrial Psychiatry Journal
|December 25, 2010
PubMed
Summary
This summary is machine-generated.

Obsessive-compulsive disorder (OCD) patients show greater cortical atrophy. Neuroimaging reveals significant differences in ventricular brain ratio (VBR), suggesting structural brain abnormalities in OCD.

Keywords:
Computerized tomography scanIntracranial structural changesNeuro-imagingObsessive-compulsive disorder

More Related Videos

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)
06:26

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)

Published on: November 27, 2019

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Related Experiment Videos

Last Updated: Jun 5, 2026

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
09:14

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)
06:26

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images (SDM-PSI)

Published on: November 27, 2019

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
09:29

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Area of Science:

  • Neuroimaging
  • Psychiatry
  • Neurology

Background:

  • Obsessive-compulsive disorder (OCD) is a complex mental health condition.
  • The underlying neurobiology of OCD is not fully understood.
  • Previous research suggests potential structural brain differences in individuals with OCD.

Purpose of the Study:

  • To investigate intracranial structural changes in patients with OCD.
  • To compare brain structure between OCD patients and healthy controls using CT scans.
  • To evaluate ventricular size, Evan's ratio, and ventricular brain ratio (VBR) in OCD.

Main Methods:

  • Thirty adult OCD patients (21-40 years) and a control group underwent CT scans.
  • Comparison focused on ventricular size, Evan's ratio, and VBR.
  • Inclusion and exclusion criteria were applied to participants.

Main Results:

  • OCD patients exhibited greater cortical atrophy, particularly in frontal and parietal areas.
  • A significant difference was observed in the mean ventricular brain ratio (VBR) between OCD patients and controls.
  • While mean Evan's ratio was lower in OCD patients, the difference was not statistically significant.

Conclusions:

  • Neuroimaging reveals structural brain abnormalities in patients with OCD.
  • Findings challenge the traditional view of OCD as purely a functional disorder.
  • Evidence supports the presence of neuro-radiological abnormalities in OCD.