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Ligand Nano-cluster Arrays in a Supported Lipid Bilayer
Published on: April 23, 2017
Enhancing cell recognition by scrutinizing cell surfaces with a nanoparticle array
Hongyu Zhou1, Peifu Jiao, Lei Yang
1Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.
Journal of the American Chemical Society
|December 25, 2010
Abstract:
We report a dual-ligand nanoparticle array approach for discerning cells that have different surface receptor profiles surrounding a common primary receptor expressed at high or low levels. The achieved differentiation provides nanoparticles the ability for potential applications in treatment of patients at a personalized medicine level for drug delivery and radiation therapy with a much better safety profile.

