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Related Experiment Video

Updated: Jun 5, 2026

Demonstrating Hairy and Glabrous Skin Innervation in a 3D Pattern Using Multiple Fluorescent Staining and Tissue Clearing Approaches

Demonstrating Hairy and Glabrous Skin Innervation in a 3D Pattern Using Multiple Fluorescent Staining and Tissue Clearing Approaches

Published on: May 20, 2022

"Hairy" granular cell tumor.

Stefano Cambiaghi¹, Laura Maffeis, Vinicio Boneschi

¹Department of Dermatology, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy. stefano.cambiaghi@fastwebnet.it

Pediatric Dermatology

|December 25, 2010

Summary

A rare solitary subcutaneous granular cell tumor with overlying hypertrichosis in a child is presented. This finding suggests granular cell tumors should be considered in pediatric differential diagnoses for skin neoplasms with hypertrichosis.

Related Experiment Videos

Last Updated: Jun 5, 2026

Demonstrating Hairy and Glabrous Skin Innervation in a 3D Pattern Using Multiple Fluorescent Staining and Tissue Clearing Approaches

Demonstrating Hairy and Glabrous Skin Innervation in a 3D Pattern Using Multiple Fluorescent Staining and Tissue Clearing Approaches

Published on: May 20, 2022

Area of Science:

Pediatric Dermatology
Surgical Pathology

Background:

Granular cell tumors (GCTs) are rare neoplasms of neural crest origin.
Cutaneous neoplasms in children require careful differential diagnosis.

Observation:

This report details a unique case of a solitary subcutaneous granular cell tumor in a pediatric patient.
The tumor presented with a distinctive feature of overlying hypertrichosis.

Findings:

The case highlights the coexistence of granular cell tumor and hypertrichosis in a child.
Histopathological confirmation is crucial for diagnosing subcutaneous granular cell tumors.

Implications:

Granular cell tumors should be included in the differential diagnosis of pediatric cutaneous neoplasms presenting with hypertrichosis.
This case expands the understanding of GCT presentation in pediatric populations.
Early and accurate diagnosis is essential for appropriate management of pediatric skin tumors.