Related Experiment Video

Updated: Aug 19, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

Published on: March 22, 2012

[Diagnosis of allergic bronchopulmonary aspergillosis]

V B Antonov, T N Golubeva, V S Mitrofanov

    Terapevticheskii Arkhiv
    |January 1, 1990
    PubMed

    Insights

    Diagnosing allergic bronchopulmonary aspergillosis (ABPA) involves high IgE levels and specific Aspergillus fumigatus sensitivity. Eosinophilia in sputum and blood suggests ABPA in patients with persistent lung issues.

    Area of Science:

    • Pulmonology
    • Allergology
    • Infectious Diseases

    Background:

    • Allergic bronchopulmonary aspergillosis (ABPA) is an inflammatory lung disease.
    • Diagnosis can be challenging, often overlapping with other respiratory conditions.

    Purpose of the Study:

    • To describe diagnostic criteria and clinical features of ABPA.
    • To highlight the importance of considering ABPA in specific patient populations.

    Main Methods:

    • Case study of five patients diagnosed with ABPA.
    • Diagnostic criteria included elevated total IgE, specific IgE to Aspergillus fumigatus, and positive skin tests.
    • Clinical evaluation of symptoms and laboratory findings.

    Main Results:

    • All patients exhibited high total IgE and specific IgE to Aspergillus fumigatus.
    • Four patients with active disease showed sputum and peripheral blood eosinophilia.
    • Two patients presented with clinical symptoms consistent with bronchial asthma.

    Conclusions:

    • Elevated IgE, specific IgE to Aspergillus fumigatus, and eosinophilia are key indicators of ABPA.
    • ABPA should be suspected in patients with chronic or relapsing lung infiltrates accompanied by eosinophilia.

    More Related Videos

    Murine Model of Allergen Induced Asthma08:05

    Murine Model of Allergen Induced Asthma

    Published on: May 14, 2012

    Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis09:52

    Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

    Published on: March 9, 2018

    Related Concept Videos

    Asthma: Pathogenesis and Management01:20

    Asthma: Pathogenesis and Management

    Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
    Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
    Pneumonia III: Complications and Assessment01:30

    Pneumonia III: Complications and Assessment

    Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
    Pulmonary Tuberculosis IV01:26

    Pulmonary Tuberculosis IV

    Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
    Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
    Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

    Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

    Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
    Medical History
    Asthma-IV: Diagnostic and Management01:30

    Asthma-IV: Diagnostic and Management

    The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
    Clinical Assessment for Asthma:
    This is the first step in diagnosing and managing asthma. It includes:
    Asthma I: Introduction01:28

    Asthma I: Introduction

    Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...