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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
Published on: March 9, 2018
A case of pulmonary aspergilloma and actinomycosis
Chen-Wei Huang1, Ming-An Lee1, Ruey-Hwa Lu2
1Division of Chest Medicine, Department of Internal Medicine, Zhongxing Branch of Taipei City Hospital, Taiwan, ROC.
Abstract:
Pulmonary aspergilloma and pulmonary actinomycosis are rare pulmonary infectious diseases. Clinical manifestations of pulmonary aspergilloma and pulmonary actinomycosis include chronic cough, fever, chest pain, haemoptysis and other pathologies, but some patients may be asymptomatic. We report a case of a healthy 33-year-old woman without any underlying diseases, who was admitted to Zhongxing Branch of Taipei City Hospital, Taiwan, for intermittent haemoptysis and right upper chest pain, which had persisted for several months. A chest radiograph revealed a focal consolidation in the right upper lobe (RUL) of the lung, which grew in size over time. A sputum study and bronchoscopy revealed no positive findings, although malignancy could not be ruled out. Thus, the patient received a wedge resection of the RUL lesion. Subsequent, pathological examination demonstrated the presence of pulmonary aspergilloma and pulmonary actinomycosis. The patient's symptoms resolved after resection of the RUL lesion.
Insights
This case report details a rare dual infection of pulmonary aspergilloma and pulmonary actinomycosis in a healthy woman. Surgical resection successfully resolved both rare lung infections and symptoms.
Area of Science:
- Pulmonology
- Infectious Diseases
- Medical Case Reports
Background:
- Pulmonary aspergilloma and pulmonary actinomycosis are uncommon pulmonary infections.
- Symptoms can range from chronic cough and hemoptysis to being asymptomatic.
Observation:
- A healthy 33-year-old woman presented with persistent hemoptysis and chest pain.
- Imaging revealed a growing consolidation in the right upper lobe.
- Initial sputum and bronchoscopy were inconclusive, raising concern for malignancy.
Findings:
- Pathological examination after wedge resection confirmed a co-infection of pulmonary aspergilloma and pulmonary actinomycosis.
- The resected lesion contained both fungal and bacterial pathogens.
Implications:
- This case highlights the importance of considering rare co-infections in pulmonary diagnoses.
- Surgical intervention can be curative for localized pulmonary aspergilloma and actinomycosis.
- Emphasizes the diagnostic challenges and successful management of these rare lung diseases.
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