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Updated: Jun 5, 2026

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
Published on: January 21, 2018
Cardio-oncology/onco-cardiology
Robert A Hong1, Takeshi Iimura, Kenneth N Sumida
1The Queen's Medical Center, Honolulu, Hawaii, USA.
Effective cancer treatment requires understanding cardio-oncology. Chemotherapy and radiation can cause cardiotoxicity, necessitating cardiovascular evaluation and monitoring for all patients undergoing cancer therapy.
Area of Science:
- Cardio-oncology
- Cardiotoxicity
- Cardiovascular Medicine
Background:
- Cancer therapies, including chemotherapy and radiation, frequently cause cardiotoxicity.
- Cardiotoxicity manifests in various forms, such as cardiac dysfunction, ischemia, arrhythmias, and pericarditis.
Purpose of the Study:
- To highlight the critical role of cardio-oncology in managing cancer patients.
- To outline the diverse cardiotoxic effects of cancer treatments.
- To emphasize the need for cardiovascular evaluation and monitoring.
Main Methods:
- Review of cardiotoxic effects associated with antineoplastic agents and radiation therapy.
- Discussion of cardiovascular evaluation protocols for cancer patients.
- Consideration of pharmacologic interventions to mitigate cardiotoxicity.
Main Results:
- All antineoplastic agents carry a risk of cardiotoxicity.
- Radiation therapy can lead to long-term cardiac damage.
- Proactive cardiovascular assessment and monitoring are essential for cancer patients.
Conclusions:
- Cardio-oncology is crucial for optimizing cancer patient care.
- Early cardiovascular evaluation and serial monitoring can detect and manage treatment-related cardiac issues.
- Collaborative care between cardiologists and oncologists is vital.
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