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Updated: Jun 5, 2026

Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
Larynx preservation: what is the standard treatment?
Samy Horn1, Mahmut Ozsahin, Jean-Louis Lefèbvre
1Academic Radiation Oncology Department, Centre Oscar Lambret, Service Academique de Radiotherapy, 3 Rue Frédéric Combemale, F-59000 Lille, France.
Abstract:
Locally advanced laryngeal and hypo-pharyngeal cancers have a rather poor prognosis. Up until the early 1990s, standard treatment was total laryngectomy, with dramatic functional and social outcome. The introduction of cisplatin based chemotherapy made concurrent chemo-radiotherapy (CCRT) the standard treatment for selected patients, fit for an organ preservation strategy. Over two decades of improvement in nonsurgical management of locally advanced laryngeal cancer is reviewed, including the most recent improvements with the introduction of taxanes and anti-EGFR targeted therapy.
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