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Updated: Jun 5, 2026
12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
[Management of gestational diabetes]
S Jacqueminet1, M-F Jannot-Lamotte
1CHU Pitié Salpêtrière, Service de diabétologie et maladies métaboliques, 47-83 Boulevard de l'hôpital, 75013 Paris, France. sophie.jacqueminet@psl.aphp.fr
Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction
|December 28, 2010
Summary
Intensive treatment for gestational diabetes mellitus (GDM) significantly reduces severe perinatal complications and fetal macrosomia. However, oral antidiabetics are not recommended due to insufficient long-term data.
Area of Science:
- Obstetrics and Gynecology
- Endocrinology
- Perinatal Medicine
Background:
- Gestational diabetes mellitus (GDM) poses risks for maternal and perinatal health.
- Intensive management strategies can mitigate these complications.
Purpose of the Study:
- To evaluate the impact of various GDM treatments, glycemic targets, and self-monitoring methods on maternal and fetal outcomes.
- To synthesize evidence on the efficacy of GDM interventions in reducing perinatal morbidity and mortality.
Main Methods:
- Systematic literature review focusing on GDM treatment efficacy.
- Bibliographic search using PubMed with keywords: "therapeutic", "treatment", and "gestational diabetes".
Main Results:
- Specific GDM treatments (diet, exercise, self-monitoring, insulin) decrease severe perinatal complications, fetal macrosomia, and pre-eclampsia compared to no treatment.
- While oral antidiabetics (glyburide, metformin) showed no adverse effects compared to insulin, they are not recommended.
- Triggered deliveries increased, but cesarean sections did not.
Conclusions:
- Treatment for moderate to severe GDM is advised.
- Further long-term studies, especially on children, are necessary before widespread use of oral antidiabetics in GDM management.
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