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Macrostachyols A-D, new oligostilbenoids from the roots of Gnetum macrostachyum
Piyawit Sri-in1, Jirapast Sichaem, Pongpun Siripong
1Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.
Fitoterapia
|December 28, 2010
Abstract:
Four new oligostilbenes, macrostachyols A-D (1-4) along with six known stilbenoids (5-10), were isolated from the roots of Gnetum macrostachyum. These compounds were also evaluated for their cytotoxicity towards HeLa and KB cell lines. Only compound 4 showed the significant cytotoxicity to HeLa cells with IC(50) value of 4.13 μM.
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