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Encapsulating peritoneal sclerosis associated with abnormal liver development in a young dog
Takeshi Izawa1, Fumi Murai, Hideo Akiyoshi
1Laboratory of Veterinary Pathology, Osaka Prefecture University, Rinku-Orai Kita, Izumisano, Osaka, Japan. izawa@vet.osakafu
The Journal of Veterinary Medical Science
|December 29, 2010
Summary
A Miniature Pinscher developed chronic ascites and intestinal adhesions due to encapsulating peritoneal fibrosis. Despite surgery, the condition recurred, leading to the dog's death, highlighting the severity of this fibrotic disease.
Area of Science:
- Veterinary Pathology
- Comparative Pathology
Background:
- Encapsulating peritoneal fibrosis (EPF) is a severe fibrotic condition affecting abdominal organs.
- This case examines EPF in a young Miniature Pinscher, a breed not commonly associated with this condition.
Observation:
- A 6-month-old Miniature Pinscher presented with chronic ascites, abdominal organ encapsulation, and intestinal adhesions.
- Surgical removal of fibrotic membranes and adhesions was performed twice, but recurrence was observed.
Findings:
- Necropsy revealed recurrent encapsulating peritoneal fibrosis with collagenous connective tissue, lymphoplasmacytic infiltration, and neovascularization.
- Fibrotic lesions extended to the serosa of multiple abdominal organs.
- The dog also exhibited a maldeveloped liver with disorganized hepatic structures.
Implications:
- This case underscores the aggressive nature of encapsulating peritoneal fibrosis in dogs.
- The findings contribute to understanding EPF pathology and its potential co-occurrence with congenital liver defects.
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