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Nasal and ocular effects in foundry workers using the hot box method.

Håkan Löfstedt1, Håkan Westberg, Anders I Seldén

  • 1Department of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden. hakan.lofstedt@orebroll.se

Journal of Occupational and Environmental Medicine
|December 29, 2010
PubMed
Summary

Foundry workers exposed to monoisocyanates showed more nasal symptoms and signs. This suggests a link between the foundry environment, including irritants like formaldehyde and dust, and respiratory issues.

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Area of Science:

  • Occupational Health
  • Environmental Medicine
  • Toxicology

Background:

  • Foundry work involves exposure to various chemicals, including monoisocyanates.
  • Potential respiratory and nasal health effects from occupational exposures are a significant concern.

Purpose of the Study:

  • To determine the prevalence of nasal and ocular symptoms and nasal signs in foundry workers exposed to monoisocyanates via the Hot Box method.
  • To assess the relationship between specific chemical exposures and observed health effects.

Main Methods:

  • A study involving 43 foundry workers and 69 referents.
  • Data collection included questionnaires, rhinologist examinations, and measurement of exposure to isocyanic acid, methyl isocyanate, formaldehyde, and total dust.

Main Results:

  • Nasal symptoms and signs were significantly associated with occupational exposure.
  • A dose-response relationship was observed between nasal symptoms and exposure to isocyanic acid, methyl isocyanate, and formaldehyde.
  • Exposed workers exhibited a higher prevalence of dry nasal mucosa compared to referents.

Conclusions:

  • Foundry workers exposed to monoisocyanates and other irritants like formaldehyde and dust show an increased prevalence of nasal symptoms and signs.
  • The foundry environment is implicated as a contributing factor to these respiratory health issues.