Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

Cardiomyopathy IV: Restrictive Cardiomyopathy

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral Stenosis II: Clinical features and Diagnostic Tests

Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...

Mitral Valve Prolapse I: Introduction

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...

Cardiomyopathy II: Dilated Cardiomyopathy

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

HuBIE: The human blood immunome encyclopedia of TCRs and BCRs in bloodstream infections and cancer.

Frontiers in immunology·2026

Same author

Germline CDK12 variants in aggressive prostate cancer.

Cancer discovery·2026

Same author

Circulating tumor DNA at baseline as a prognostic marker in untreated follicular lymphoma.

Haematologica·2026

Same author

Identification of Compound Heterozygous CYP11A1 Variants via Reanalysis of Clinical Sequencing Data.

American journal of medical genetics. Part A·2025

Same author

HuBIE: The Human Blood Immunome Encyclopedia Of TCRs and BCRs in Bloodstream Infections and Cancer.

bioRxiv : the preprint server for biology·2025

Same author

Cross-Platform Methylation-Based Site of Origin Classification for Squamous Cell Carcinomas.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2025

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

A colossal atrial myxoma.

Atoosheh Rohani¹, Vahid Akbari

¹Yasuj University of Medical Science, Yasuj, Iran.

Journal of Cardiovascular Disease Research

|December 29, 2010

Summary

This report details a giant atrial myxoma, the most common benign heart tumor. This large cardiac tumor presented atypically, mimicking other serious heart conditions.

Area of Science:

Cardiology
Oncology
Pathology

Background:

Atrial myxomas are the most common primary cardiac tumors, typically benign.
These tumors can present with nonspecific symptoms, potentially mimicking other cardiac conditions like mitral stenosis or infective endocarditis.

Observation:

A 35-year-old male presented with vague symptoms suggestive of cardiac issues.
Echocardiography identified a large mass within the left atrium, characteristic of an atrial myxoma.

Findings:

Surgical excision revealed a giant left atrial myxoma measuring 14 × 8 × 6 cm³.
The tumor was attached to a 4 × 3 × 2 cm³ stalk of septal tissue.

Implications:

This case highlights the potential for atrial myxomas to grow to exceptional sizes.

Keywords:

Hypesthesia myxomas vertigo

More Related Videos

Isolation of Atrial Myocytes from Adult Mice

Isolation of Atrial Myocytes from Adult Mice

Published on: July 25, 2019

Related Experiment Videos

Last Updated: Jun 5, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Isolation of Atrial Myocytes from Adult Mice

Isolation of Atrial Myocytes from Adult Mice

Published on: July 25, 2019

The rarity of such a large myxoma underscores the importance of thorough diagnostic evaluation for cardiac masses.

Reporting this giant myxoma contributes to the literature on cardiac tumors and their clinical presentation.