Related Experiment Video
Updated: Jun 5, 2026

LAD-Ligation: A Murine Model of Myocardial Infarction
Published on: October 14, 2009
"MacCallum Plaque of the Heart": A Medicolegal Case
Udasimath Shivakumarswamy1, Sankappa P Sinhasan, R Purushotham
1Department of Pathology, Hassan Institute of Medical Sciences, Karnataka, India.
Abstract:
Mural endocardial lesions can be seen as MacCallum plaques in rheumatic heart disease. These plaques appear as map-like areas of thickened, roughened, and wrinkled part of the endocardium in the left atrium. Perhaps they are caused by regurgitant jets of blood flow, due to incompetence of the mitral valve. Although MacCallum plaques are one of the characteristic features in rheumatic heart disease, they are very uncommon in recent times. We hereby report a case of an adolescent female with RHD, who was working as a housemaid in a doctor's house for a few months, and suddenly developed respiratory tract infection and cardiac failure. She died on the fourth day of admission. A medicolegal autopsy was conducted, as her relatives accused her master of sexual assault. On autopsy it was seen that the mitral valves were narrowed, showing multiple vegetations. MacCallum plaque was seen in the dilated left atrium. Hence, it is presented here for educative purposes.
More Related Videos
Related Concept Videos
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome III: Diagnostic Studies
Cardiomyopathy II: Dilated Cardiomyopathy
Coronary Artery Disease II: Pathophysiology

