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Monilethrix in pattern distribution in siblings: diagnosis by trichoscopy
1Department of Dermatology, Seth G S Medical College and KEM Hospital, Mumbai, Maharashtra, India.
International Journal of Trichology
|December 29, 2010
Summary
Monilethrix, a rare genetic hair disorder, can be diagnosed using trichoscopy, a non-invasive technique. This study highlights its utility in identifying characteristic hair shaft abnormalities, aiding early diagnosis in affected siblings.
Area of Science:
- Genetics
- Dermatology
- Trichology
Background:
- Monilethrix is an inherited hair shaft disorder causing alopecia and follicular keratosis.
- Diagnosis typically relies on microscopic examination of hair shafts.
- Macroscopic features for rapid diagnosis are lacking.
Observation:
- Two Indian male siblings presented with scalp hair thinning and follicular papules.
- Clinical presentation suggested male pattern hair loss and monilethrix.
- Trichoscopy revealed characteristic beaded hair shafts and follicular abnormalities.
Findings:
- Trichoscopy confirmed monilethrix with uniform elliptical nodes and constrictions.
- Dermoscopy of papules showed broken hair stubs with a beaded appearance.
- Diagnosis was supported by light microscopy and hair clipping.
Implications:
- Trichoscopy is a valuable, non-invasive tool for diagnosing monilethrix.
- Patterned hair loss in monilethrix may be linked to early androgenetic alopecia.
- Early diagnosis facilitates appropriate management and genetic counseling.
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