Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Characterization of interfaces in human calcified tissue.

M Martin1, A Lamure, C Lacabanne

  • 1Laboratoire de Physique des Solides, URA/CNRS 74, Université de Toulouse, France.

Biomaterials
|July 1, 1990
PubMed
Summary

Thermostimulated current spectroscopy reveals molecular mobility in human calcified tissues. This study identifies the organic-mineral complex interphase response during demineralization.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term performance of a low-modulus acrylic cement in a simulated physiological environment.

Medical engineering & physics·2025
Same author

Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain.

Nature communications·2020
Same author

Maternal dietary omega-3 deficiency worsens the deleterious effects of prenatal inflammation on the gut-brain axis in the offspring across lifetime.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2020
Same author

Chain dynamics of human dermis by Thermostimulated currents: A tool for new markers of aging.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2018
Same author

Identification of ageing biomarkers in human dermis biopsies by thermal analysis (DSC) combined with Fourier transform infrared spectroscopy (FTIR/ATR).

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2017
Same author

Conformational and thermal characterization of left ventricle remodeling post-myocardial infarction.

Biochimica et biophysica acta. Molecular basis of disease·2017

Area of Science:

  • Biophysics
  • Materials Science
  • Biochemistry

Background:

  • Human calcified tissues possess complex organic-mineral structures.
  • Understanding molecular mobility is crucial for tissue health and disease.
  • Demineralization alters the structural and molecular properties of these tissues.

Purpose of the Study:

  • To investigate molecular mobility within human calcified tissues using Thermostimulated Current (TSC) spectroscopy.
  • To comparatively analyze tissue extracts at different stages of demineralization.
  • To identify the specific response of the organic-mineral complex interphase.

Main Methods:

  • Thermostimulated Current (TSC) spectroscopy was employed.
  • Human calcified tissue samples were subjected to varying degrees of demineralization.

Related Experiment Videos

  • Extracts from these samples were analyzed to assess molecular dynamics.

    • Main Results:

    • TSC spectroscopy successfully detected molecular mobility in human calcified tissues.
    • Distinct responses were observed in extracts corresponding to different demineralization stages.
    • The characteristic response of the organic-mineral complex interphase was identified.

    Conclusions:

    • Thermostimulated Current spectroscopy is a viable method for studying molecular mobility in calcified tissues.
    • Demineralization significantly impacts the molecular dynamics and interphase behavior.
    • The findings provide insights into the structural integrity and changes in human calcified tissues.