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Updated: Jun 5, 2026

Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
Rituximab administration and reactivation of HBV
Yutaka Tsutsumi1, Reiki Ogasawara, Yusuke Kamihara
1Department of Hematology, Hakodate Municipal Hospital, Hakodate 041-8680, Japan.
Abstract:
Rituximab is a drug used for the treatment of B-cell non-Hodgkin's lymphoma, and its range of use has expanded to the treatment of collagen diseases such as idiopathic thrombocytopenic purpura and rheumatoid arthritis. One serious complication of rituximab use is the reactivation of dormant hepatitis B virus, and prevention of this phenomenon has become an urgent issue. This paper provides a general outline of the problem through an analysis of patient cases that we and other groups have experienced to date.
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