[Changes in hypothalamic-pituitary-gonadal function in male patients with acute attack of chronic cor pulmonale]

Contents of serum luteinizing hormone, follicle-stimulating hormone, and plasma testosterone and estradiol in 50 male patients with acute attack of chronic cor pulmonale and in 26 healthy men were determined using the method of radioimmunoassay, and the response of pituitary gonadotropins to luteinizing hormone-releasing hormone (LHR) was measured. Analysis of the results suggested that there are greatly disturbances of hypothalamic-pituitary-gonadal function in male patients with acute attack of chronic cor pulmonale, and that hypoxemia is an important factor leading to this disorder.