Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydrological disasters and health losses: an index-based analysis for Brazil.

Revista de saude publica·2026
Same author

Tracking of dietary patterns from early childhood to school age in the Brazilian Food and Nutritional Surveillance System, 2008-2019.

Public health nutrition·2026
Same author

Impact of a non-contributory pension for older adults on hospitalisations and mortality: a protocol for a natural experimental study of the Brazilian continuous cash benefit (BPC).

BMJ open·2026
Same author

Road safety policies and motor vehicle fatalities in Ecuador: a geographical and temporal analysis from 1990 to 2022.

BMJ public health·2026
Same author

Premature mortality due to non-communicable diseases and deprivation in a Brazilian state capital.

Ciencia & saude coletiva·2026
Same author

Obesity and Oral Health-Related Quality of Life: An Exploratory Analysis of Associated Factors.

Oral diseases·2026

Related Experiment Video

Updated: Jun 5, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Chronic periodontitis and C-reactive protein levels.

Isaac Suzart Gomes-Filho1, Julita Maria Freitas Coelho, Simone Seixas da Cruz

  • 1Department of Health, Feira de Santana State University, Feira de Santana, BA, Brazil.

Journal of Periodontology
|December 30, 2010
PubMed
Summary

Chronic periodontitis is linked to higher C-reactive protein (CRP) levels, a marker of inflammation. This association persists even when accounting for factors like age, smoking, and diabetes.

Related Experiment Videos

Last Updated: Jun 5, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

Area of Science:

  • Periodontology
  • Cardiovascular Medicine
  • Biomarkers of Inflammation

Background:

  • Chronic periodontitis is a prevalent inflammatory condition.
  • Cardiovascular disease (CVD) shares inflammatory pathways.
  • Understanding the link between periodontitis and systemic inflammation is crucial.

Purpose of the Study:

  • To investigate the association between chronic periodontitis and C-reactive protein (CRP) levels.
  • To explore this relationship in individuals with and without cardiovascular disease.
  • To identify confounding variables influencing the periodontitis-CRP association.

Main Methods:

  • A cohort of 359 adults (≥40 years) was assessed, including patients with acute myocardial infarction, other hospital admissions, and community dwellers.
  • Data collection involved questionnaires for demographics/lifestyle, periodontal examinations, anthropometric measurements, and blood tests (CRP, glucose, lipids).
  • Logistic regression analysis was employed to determine associations, adjusting for potential confounders.

Main Results:

  • Individuals with chronic periodontitis exhibited significantly higher mean CRP levels compared to those without periodontitis.
  • Chronic periodontitis was independently associated with elevated CRP levels (aOR: 2.26; 95% CI: 1.30–3.93).
  • This association remained significant after adjusting for age, education, sex, smoking, HDL cholesterol, and diabetes.

Conclusions:

  • Chronic periodontitis is significantly associated with elevated plasma CRP levels.
  • The findings highlight a potential systemic inflammatory link between periodontal infection and CRP.
  • These results underscore the importance of considering periodontal health in systemic disease management.