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The interferon stimulated gene 54 promotes apoptosis

Marcin Stawowczyk1, Sarah Van Scoy, K Prasanna Kumar

  • 1Department of Molecular Genetics and Microbiology, Stony Brook University Stony Brook, New York 11794, USA.

The Journal of Biological Chemistry
|December 31, 2010
PubMed
Summary

Interferon-stimulated gene 54 (ISG54/IFIT2) directly induces apoptosis, a programmed cell death. This finding reveals a new mechanism for interferon's anti-viral and anti-cancer functions.

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