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Benign lumbar arachnoiditis: MR imaging with gadopentetate dimeglumine
1Sloan-Kettering Cancer Center, New York, NY.
Abstract:
MR imaging was performed in 13 patients with benign lumbar arachnoiditis both before and after IV injection of gadopentetate dimeglumine. The arachnoiditis was proved by previous myelography in 12 patients and by noncontrast MR imaging in one patient. The disease was presumably the result of previous myelography and/or surgery. It was characterized as mild in two patients, moderate in two patients, and severe in nine patients. Imaging was performed on a 1.5-T unit, and both short and long TR images were obtained before and after contrast administration. Noncontrast MR images demonstrated changes consistent with arachnoiditis in all patients. After contrast, three patients had no enhancement, three patients had minimal enhancement, three patients had mild enhancement, and four patients had moderate enhancement. In no case did contrast enhancement alter the diagnosis or reveal additional findings that could not be seen on the noncontrast images. Gadopentetate dimeglumine enhancement plays little role in the diagnosis of lumbar arachnoiditis. If used for another reason, however, short TR scans may show enhancement of adherent roots in some cases. In addition, administration of gadopentetate dimeglumine will not cause sufficient enhancement to hinder the detection of arachnoiditis on long TR images and may aid in recognition of adherent roots on short TR images.
Insights
Gadolinium contrast (gadopentetate dimeglumine) does not improve diagnosis of lumbar arachnoiditis on MRI scans. Noncontrast MRI effectively identifies arachnoiditis, with contrast offering minimal diagnostic value.
Area of Science:
- Radiology
- Neurology
- Medical Imaging
Background:
- Lumbar arachnoiditis is a condition affecting the spinal cord's protective layers.
- Previous myelography and/or surgery are presumed causes of this condition.
Purpose of the Study:
- To evaluate the diagnostic utility of gadolinium-enhanced MRI (gadopentetate dimeglumine) in patients with lumbar arachnoiditis.
- To determine if contrast administration alters diagnosis or reveals additional findings compared to noncontrast MRI.
Main Methods:
- 13 patients with confirmed benign lumbar arachnoiditis underwent 1.5-T MRI.
- Scans were performed before and after intravenous gadopentetate dimeglumine injection.
- Both short and long TR (repetition time) image sequences were acquired.
Main Results:
- Noncontrast MRI demonstrated arachnoiditis in all patients.
- Contrast enhancement was observed in varying degrees (minimal to moderate) in 10 out of 13 patients.
- Contrast administration did not alter the diagnosis or reveal new findings not visible on noncontrast images.
Conclusions:
- Gadopentetate dimeglumine enhancement has limited diagnostic value for lumbar arachnoiditis.
- Noncontrast MRI is sufficient for diagnosing lumbar arachnoiditis.
- Contrast may aid in visualizing adherent nerve roots on short TR sequences but does not hinder detection on long TR sequences.