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Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
Published on: October 27, 2014
Response to temozolomide and bevacizumab in a patient with poorly differentiated neuroendocrine carcinoma
Daniel P Lindholm1, Barbro Eriksson, Dan Granberg
1Department of Endocrine Oncology, Uppsala University Hospital, 75185 Uppsala, Sweden. daniel.lindholm@medsci.uu.se
Abstract:
Poorly differentiated endocrine carcinomas (PDEC) are usually treated with cisplatin-based chemotherapy regimens. We here present a case with a dramatic response (both radiologically and biochemically) to the combination of temozolomide and bevacizumab, after failure of cisplatin and etoposide, with continued tumor shrinkage at 5 months. Temozolomide combined with bevacizumab might be a good treatment option in PDEC, perhaps even in a first-line setting. Prospective studies to answer this are warranted.
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