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Updated: Jun 5, 2026
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Published on: March 17, 2026
Is modified Devine exclusion necessary for gastrojejunostomy in patients with unresectable pancreatobiliary cancer?
Teruyuki Usuba1, Takeyuki Misawa, Yoichi Toyama
1Department of Surgery, Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minato-ku, Tokyo 105-8461, Japan.
Purpose:
Gastrojejunostomy is often performed as palliative surgery for unresectable pancreatobiliary cancer. Modified Devine exclusion (MDE) is a technical variation of gastrojejunostomy, which partially separates the mid-portion of the stomach. We conducted this study to assess whether MDE is necessary for gastrojejunostomy in patients with unresectable pancreatobiliary cancer.
Methods:
We compared the postoperative results of MDE (n = 26) with those of conventional gastrojejunostomy (CGJ; n = 20) performed palliatively for unresectable pancreatobiliary cancers.
Results:
The morbidity rates were 38% after MDE and 50% after CGJ, with 23% and 40% of patients suffering delayed gastric emptying, respectively. Two of the CGJ group patients could never eat again. Modified Devine exclusion slowed the progression of anemia in all of the patients with duodenal bleeding.
Conclusion:
Modified Devine exclusion may be effective for patients with unresectable pancreatobiliary cancer.
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