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Synthesis of 3-aryl-2-substituted-4(3H)-quinazolines as potential antimicrobial agents
A M Farghaly1, A Mohsen, M E Omar
1Departement of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Egypt.
Farmaco (Societa Chimica Italiana : 1989)
|April 1, 1990
Abstract:
Three new series of 4(3H)-quinazolinone derivatives were synthesized, namely: [3-Aryl-4(3H)-quinazolinon-2-yl]-methylenehydrazino-(N- substituted)-thiocarbamides, 3-Aryl-2-(3-substituted-4-phenyl-2,3-dihydrothiazol-2-ylidenehy drazonomethyl)-4 (3H)-quinazolinones and 3-Aryl-2-(3-substituted-4-oxothiazolidin-2-ylidenehydrazonometh yl)-4(3H)-quinazolinones. The antimicrobial activities of the synthesized compounds were also studied.