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Detection of Foodborne Bacterial Pathogens from Individual Filth Flies
Published on: February 13, 2015
Foodborne illness acquired in the United States--unspecified agents
Elaine Scallan1, Patricia M Griffin, Frederick J Angulo
1Centers for Disease Control and Prevention, Atlanta, Georgia, USA. elaine.scallan@ucdenver.edu
Abstract:
Each year, 31 major known pathogens acquired in the United States caused an estimated 9.4 million episodes of foodborne illness. Additional episodes of illness were caused by unspecified agents, including known agents with insufficient data to estimate agent-specific illness, known agents not yet recognized as causing foodborne illness, substances known to be in food but of unproven pathogenicity, and unknown agents. To estimate these additional illnesses, we used data from surveys, hospital records, and death certificates to estimate illnesses, hospitalizations, and deaths from acute gastroenteritis and subtracted illnesses caused by known gastroenteritis pathogens. If the proportions acquired by domestic foodborne transmission were similar to those for known gastroenteritis pathogens, then an estimated 38.4 million (90% credible interval [CrI] 19.8-61.2 million) episodes of domestically acquired foodborne illness were caused by unspecified agents, resulting in 71,878 hospitalizations (90% CrI 9,924-157,340) and 1,686 deaths (90% CrI 369-3,338).
Insights
Unspecified agents cause millions of foodborne illnesses annually in the US. These unknown or poorly understood pathogens lead to an estimated 38.4 million foodborne illnesses, resulting in significant hospitalizations and deaths.
Area of Science:
- Foodborne illness epidemiology
- Microbial risk assessment
- Public health surveillance
Background:
- 31 major known pathogens cause 9.4 million foodborne illnesses yearly in the US.
- Additional illnesses stem from unspecified agents, including those with limited data or unproven pathogenicity.
- Acute gastroenteritis is a significant public health concern with multiple causative agents.
Purpose of the Study:
- To estimate the burden of foodborne illness caused by unspecified agents in the United States.
- To quantify hospitalizations and deaths attributed to these unspecified foodborne pathogens.
- To provide a more comprehensive understanding of the total foodborne illness landscape.
Main Methods:
- Utilized data from surveys, hospital records, and death certificates.
- Estimated total illnesses, hospitalizations, and deaths from acute gastroenteritis.
- Subtracted illnesses attributed to known gastroenteritis pathogens to isolate those from unspecified agents.
- Assumed similar domestic foodborne transmission proportions for unspecified agents as for known pathogens.
Main Results:
- An estimated 38.4 million episodes of domestically acquired foodborne illness were caused by unspecified agents.
- These illnesses resulted in 71,878 hospitalizations.
- An estimated 1,686 deaths were linked to foodborne illness from unspecified agents.
Conclusions:
- Unspecified agents represent a substantial, underestimated burden of foodborne illness in the US.
- Further research is needed to identify and characterize these agents to mitigate public health risks.
- Current estimates highlight the importance of broad food safety measures beyond known pathogens.
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