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Synthesis and bio-evaluation of aryl hydrazono esters for oviposition responses in Aedes albopictus
Prabal Bandyopadhyay1, Lopamudra Guha, T Seenivasagan
1Defence R & D Establishment, Jhansi Road, Gwalior 474 002 (M.P.), India.
Abstract:
A novel series of aryl hydrazono esters (AHE) (1-13) were synthesized (yield 76-98%) to study the oviposition responses in Aedes albopictus (Skuse) mosquitoes for the first time. At a concentration of 10μgml(-1) in dual choice experiment, among the screened compounds, AHE-12 showed remarkable oviposition attractant activity with an oviposition activity index (OAI) of +0.299 (greater than 95% confidence limit) comparable to p-cresol (OAI +0.320) which is well-reported oviposition attractant for Aedes aegypti. Conversely, AHE-10 exhibited highest oviposition deterrent activity with OAI -0.247. The possible utilization of these compounds will be in integrated vector management strategies.
