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Complications of mechanical ventilation in the pediatric population
Tania Principi1, Douglas D Fraser, Gavin C Morrison
1Critical Care Unit, Children's Hospital, London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada.
Background:
Mechanical ventilation (MV) strategies are continuously evolving in an effort to minimize adverse events. The objective of this study was to determine the complications associated with MV in children.
Study Design:
Prospective observational study. Over a period of 10 consecutive months, 150 patients (median age 0.8 years, IQR 4.4, 59% male) were enrolled in this study.
Results:
The median duration of MV was 3.1 days (IQR 3.9). A total of 85 complications were observed in 60 (40%) patients (114 complications per 1,000 ventilation days). 16.7% of patients developed atelectasis, 13.3% post-extubation stridor, 9.3% failed extubation, 2.0% pneumothorax, 3.3% accidental extubation, 2.7% nasal or perioral tissue damage and 1.9% ventilator associated pneumonia. Atelectasis occurred most often in the left lower lobe (36%) or in the right upper lobe (26%). The incidence of atelectasis in children <1 year of age was 12% (31 episodes per 1,000 days of ventilation) compared to 18% (57 episodes per 1,000 days of ventilation) in children ≥ 1 year of age (P < 0.05). Patients that failed extubation were ventilated for a median of 8.5 (IQR 8.8) days compared to 2.9 days (IQR, 3.8) in patients that were successfully extubated (P < 0.01). The absence of an air leak prior to extubation did not correlate with failed extubation. Accidental extubation was limited to orally intubated patients.
Conclusion:
MV complications occurred in 40% of patients and most often consisted of atelectasis and post-extubation stridor. Further studies are needed to examine associated risk factors and strategies to reduce their occurrence.
Insights
Mechanical ventilation (MV) complications occurred in 40% of pediatric patients, with atelectasis and post-extubation stridor being most common. Further research is needed to identify risk factors and reduction strategies for these adverse events.
Area of Science:
- Pediatric critical care medicine
- Respiratory therapy
- Clinical research methodology
Background:
- Mechanical ventilation (MV) is essential for critically ill children but carries risks.
- Evolving MV strategies aim to minimize adverse events.
- Understanding pediatric MV complications is crucial for improving patient outcomes.
Purpose of the Study:
- To determine the incidence and types of complications associated with mechanical ventilation in children.
- To identify specific adverse events linked to MV in a pediatric population.
Main Methods:
- Prospective observational study design.
- Enrolled 150 pediatric patients over 10 months (median age 0.8 years).
- Monitored patients for complications during mechanical ventilation.
Main Results:
- 40% of patients experienced MV complications (85 total events).
- Most common complications included atelectasis (16.7%), post-extubation stridor (13.3%), and failed extubation (9.3%).
- Atelectasis was more frequent in children aged 1 year or older; failed extubation was associated with longer ventilation duration.
Conclusions:
- Mechanical ventilation in children is associated with significant complication rates.
- Atelectasis and post-extubation stridor are the predominant complications.
- Further investigation into risk factors and preventative strategies is warranted.
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