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Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies

Published on: January 16, 2019

Duration of preceding hypertension is associated with prolonged length of ICU stay

Julie S Sanders1, James R A Skipworth, Jackie A Cooper

  • 1Department of Surgery and Interventional Science, University College London, London, UK. j.sanders@ucl.ac.uk

International Journal of Cardiology
|January 4, 2011
PubMed

Insights

Prolonged intensive care unit stay (PLOS) and mechanical ventilation (PMV) after coronary artery bypass grafting (CABG) are common. Preceding hypertension duration independently predicted PLOS, while age, diabetes, prior MI, NYHA class, and statin use predicted PMV.

Area of Science:

  • Cardiovascular Surgery
  • Intensive Care Medicine
  • Clinical Outcomes Research

Background:

  • Prolonged length of intensive care unit stay (PLOS) and prolonged mechanical ventilation (PMV) affect a significant number of patients post-coronary artery bypass grafting (CABG).
  • Identifying predictive factors for PLOS and PMV is crucial for effective patient risk stratification and resource management.

Purpose of the Study:

  • To identify independent clinical factors associated with prolonged length of intensive care unit stay (PLOS) and prolonged mechanical ventilation (PMV) in patients undergoing coronary artery bypass grafting (CABG).

Main Methods:

  • Prospective observational study of 439 patients undergoing first-time elective CABG.
  • Clinical data were collected, and PLOS was defined as >2 days and PMV as >12 hours, based on center norms.

Main Results:

  • 23.9% of patients experienced PLOS and 25.2% experienced PMV.
  • Independent predictors for PMV included age, diabetes, previous myocardial infarction (MI), New York Heart Association (NYHA) class, and statin use.
  • The duration of preceding hypertension was the sole independent predictor identified for PLOS.

Conclusions:

  • Factors predicting PMV and PLOS are routine clinical data, potentially integrable into bed management algorithms.
  • Further investigation into the mechanism linking preceding hypertension to PLOS is recommended.
Abstract

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