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Updated: Jun 5, 2026

Assessing Tumor Microenvironment of Metastasis Doorway-Mediated Vascular Permeability Associated with Cancer Cell Dissemination using Intravital Imaging and Fixed Tissue Analysis
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Tight junctions in cancer metastasis.

Tracey A Martin1, Malcolm D Mason, Wen G Jiang

  • 1Metastasis and Angiogenesis Research Group, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK. martinta1@cf.ac.uk

Frontiers in Bioscience (Landmark Edition)
|January 4, 2011
PubMed
Summary

Tight junctions (TJ) maintain cell integrity and control diffusion. Altered TJ expression impacts barrier function, driving cancer progression and metastasis.

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