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Updated: Jun 5, 2026

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Toddlers - Resting and Developmental Challenges
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Published on: February 25, 2016

Assessing autonomic dysfunction symptoms in children: a pilot study.

Xue Ming1, Jennifer M Bain, Douglas Smith

  • 1Department of Neurosciences and Neurology, New Jersey Medical School, Newark, NJ, USA. mingxu@umdnj.edu

Journal of Child Neurology
|January 4, 2011
PubMed
Summary
This summary is machine-generated.

The Pediatric Autonomic Symptoms Scale effectively identifies autonomic dysfunction in children with familial dysautonomia and autism spectrum disorders. This scale can differentiate between these neurodevelopmental disorders and controls, aiding in diagnosis.

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Area of Science:

  • Pediatric Neurology
  • Neurodevelopmental Disorders
  • Autonomic Nervous System Function

Background:

  • Autonomic dysfunction is increasingly recognized in pediatric neurodevelopmental disorders.
  • Differentiating autonomic symptoms in conditions like familial dysautonomia and autism spectrum disorders is clinically important.
  • Validated screening tools are needed to assess autonomic dysfunction in children.

Purpose of the Study:

  • To evaluate the Pediatric Autonomic Symptoms Scale as a screening tool for autonomic dysfunction.
  • To compare symptom profiles between children with familial dysautonomia, autism spectrum disorders, and controls.
  • To assess the scale's ability to distinguish between these groups.

Main Methods:

  • The Pediatric Autonomic Symptoms Scale was administered to parents of children in three groups: familial dysautonomia, autism spectrum disorders, and age-matched controls.
  • Total scores were compared across groups for each section and overall.
  • Concordance rates for symptom presence and absence were analyzed.

Main Results:

  • The Pediatric Autonomic Symptoms Scale successfully distinguished controls from children with familial dysautonomia and autism spectrum disorders.
  • Children with familial dysautonomia showed higher scores in visceral symptoms.
  • Children with autism spectrum disorders exhibited higher scores in psychosocial symptoms.

Conclusions:

  • The Pediatric Autonomic Symptoms Scale is a comprehensive tool for profiling autonomic dysfunction in familial dysautonomia and autism spectrum disorders.
  • The scale demonstrates utility in differentiating between these neurodevelopmental conditions.
  • Further research is warranted to explore its application in other pediatric disorders.