Related Experiment Video
Updated: Jun 5, 2026
Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
Published on: February 19, 2022
A new method for intraluminal gastrointestinal stromal tumor resection using laparoscopic seromuscular dissection
Kazuaki Tanabe1, Yuji Urabe, Noriaki Tokumoto
1Department of Surgery, Division of Frontier Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan. ktanabe2@hiroshima-u.ac.jp
Introduction:
It is difficult to confirm the location of an intraluminal gastrointestinal stromal tumor (GIST) and to laparoscopically determine the appropriate resection line. We report a new technique for the resection of GISTs using the laparoscopic seromuscular dissection (LSD) technique, which can be preformed regardless of the tumor location.
Methods:
Since 2009, 5 patients have undergone LSD technique for the resection of an intraluminal GIST. The tumor location was confirmed endoscopically, and the exact resection line was marked laparoscopically. After 10% glycerin was injected into the submucosal layer, LSD was performed circumferentially. The tumor was exteriorized into the abdominal cavity and dissected using a linear stapling device.
Results:
The average operation time for this procedure was 134.4 ± 18.6 min, and the mean estimated blood loss was 10 ± 8.9 ml. None of the 5 cases required open surgery. There was no tumor rupture or disruption or any other perioperative complications using this technique.
Conclusion:
We conclude that the LSD technique may be a safe and minimally invasive method for the resection of intraluminal GISTs, regardless of the tumor location.