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Related Concept Videos

Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
The Parathyroid Glands00:59

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
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Related Experiment Video

Updated: Jun 5, 2026

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
10:10

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms

Published on: April 17, 2026

Ectopic hidradenoma papilliferum.

Aristóteles David Neiva Rosmaninho1, Maria Teresa Duarte Pinto de Almeida, Vírgilio Costa

  • 1Departamento de Dermatologia, Centro Hospitalar do Porto, HSA, Edifício das Consultas Externas, Ex-CICAP, Rua D. Manuel II, 4099-001 Porto, Portugal.

Dermatology Research and Practice
|January 4, 2011
PubMed
Summary

Hidradenoma papilliferum, a rare skin tumor typically found in women, can exceptionally occur in men on the eyelid. This case highlights a rare ectopic presentation of hidradenoma papilliferum in an unusual location.

Related Experiment Videos

Last Updated: Jun 5, 2026

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
10:10

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms

Published on: April 17, 2026

Area of Science:

  • Dermatopathology
  • Oncology

Background:

  • Hidradenoma papilliferum is a rare benign adnexal tumor.
  • It predominantly affects the anogenital region of females.

Observation:

  • A 26-year-old male presented with a slow-growing nodule on his right eyelid.
  • The lesion was asymptomatic, firm, mobile, and well-demarcated.

Findings:

  • Histopathological examination confirmed the diagnosis of hidradenoma papilliferum.
  • This represents a rare ectopic (nongenital) occurrence of the tumor.
  • Eyelid localization is exceptionally infrequent among reported ectopic cases.

Implications:

  • This case expands the known clinical spectrum of hidradenoma papilliferum.
  • It underscores the importance of considering rare diagnoses in atypical locations.
  • Further research may elucidate the pathogenesis of ectopic hidradenoma papilliferum.