Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Menopause01:28

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral stimuli,...
Hormonal Regulation01:33

Hormonal Regulation

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
Hormonal Regulation01:40

Hormonal Regulation

Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence01:22

Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence

Generic intravenous (IV) drugs are considered bioequivalent to their branded counterparts due to their 100% bioavailability upon administration. However, variations in stability among different drug products can significantly influence their therapeutic performance, even if they are pharmaceutically equivalent.Cefuroxime, a prophylactic antimicrobial, is often used as a single-dose IV injection for patients undergoing coronary artery bypass grafting surgery. A 3 g dose typically provides...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Menopausal hormone therapy and pulmonary diseases.

Climacteric : the journal of the International Menopause Society·2026
Same author

Evaluation of breast risk at menopause: what impact on the use of menopausal hormone therapy?

Maturitas·2026
Same author

Evidence for actions of estrone distinct from those of estradiol.

The Journal of clinical endocrinology and metabolism·2026
Same author

Letter to the editor about the article "relationship between menopausal hormone therapy and incidence risk of breast cancer: systematic review and meta-analysis".

Annals of medicine·2026
Same author

Menopausal hormone treatment and breast cancer.

The lancet. Diabetes & endocrinology·2026
Same author

French protocol for the diagnosis and management of hereditary angioedema.

La Revue de medecine interne·2025

Related Experiment Video

Updated: Jun 5, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

[Hormone replacement therapy in France 5 years after the decrease in use].

Anne Gompel1

  • 1Unité de gynécologie endocrinienne, Hôtel-Dieu de Paris Université Paris-Descartes, 75181 Paris Cedex 4. anne.gompel@htd.aphp.fr

La Revue Du Praticien
|January 5, 2011
PubMed
Summary
This summary is machine-generated.

Following the Women's Health Initiative trial, Hormone Replacement Therapy (HRT) use declined significantly. This analysis examines current HRT practices in France and explores potential links to reduced breast cancer incidence.

More Related Videos

Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model
05:32

Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model

Published on: August 11, 2023

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

Related Experiment Videos

Last Updated: Jun 5, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
06:18

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause

Published on: August 13, 2019

Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model
05:32

Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model

Published on: August 11, 2023

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

Area of Science:

  • Endocrinology
  • Oncology
  • Public Health

Background:

  • The 2002 Women's Health Initiative (WHI) trial results led to a significant decrease in Hormone Replacement Therapy (HRT) prescriptions.
  • The widespread publicity and regulatory recommendations following the WHI trial impacted HRT utilization.
  • The long-term consequences of these changes in HRT prescribing patterns remain incompletely understood.

Purpose of the Study:

  • To document the current types of Hormone Replacement Therapy (HRT) treatments being utilized in France.
  • To offer an interpretation of the observed decrease in breast cancer incidence in relation to HRT use.

Main Methods:

  • Review of current Hormone Replacement Therapy (HRT) prescription data in France.
  • Analysis of epidemiological trends in breast cancer incidence.
  • Correlation of HRT usage patterns with breast cancer incidence data.

Main Results:

  • Characterization of contemporary HRT regimens prescribed in France.
  • Observation of a reported decrease in breast cancer incidence across Western countries post-WHI.
  • Exploration of potential causal or correlative links between HRT trends and breast cancer rates.

Conclusions:

  • Current Hormone Replacement Therapy (HRT) practices in France reflect a shift post-WHI trial.
  • The decrease in breast cancer incidence may be influenced by changes in HRT utilization.
  • Further research is warranted to fully elucidate the complex relationship between HRT and breast cancer outcomes.