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Updated: Jun 5, 2026

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
Published on: January 29, 2019
Fixed dose (555 MBq; 15 mCi) radioiodine for the treatment of hyperthyroidism: outcome and its predictors
S K Gupta1, S McGrath, K Rogers
1Department of Nuclear Medicine and PET, John Hunter Hospital, Centre for Clinical Epidemiology and Biostatistics, University of Newcastle, Newcastle, New South Wales, Australia. sandeep_kr_gupta@rediffmail.com
Abstract:
Radioiodine therapy (RIT) is an accepted treatment for hyperthyroidism and a 555-MBq (15-mCi) dose is frequently used. We aimed to assess treatment outcome with this dose, and to identify predictors of successful treatment. An analysis of 478 treated patients demonstrated an overall four-month cure rate of 79.5%; success rate was higher in patients with toxic multinodular goitre, solitary toxic adenoma, a smaller thyroid or less severe disease. This information may be of further assistance if variation in the dose of RIT is considered.
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