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Published on: March 23, 2013
Diabetic gastroparesis-backwards and forwards
Jessica Chang1, Christopher K Rayner, Karen L Jones
1University of Adelaide Discipline of Medicine, Royal Adelaide Hospital, South Australia, Australia.
Journal of Gastroenterology and Hepatology
|January 5, 2011
Summary
Diabetic gastroparesis, once considered rare, is now understood to impact diabetes management. This review details 25 years of research on gastric emptying and blood glucose regulation in diabetic patients.
Area of Science:
- Gastroenterology
- Endocrinology
- Diabetology
Background:
- Diabetic gastroparesis was historically underestimated, linked solely to type 1 diabetes and severe neuropathy.
- A 1986 study by Horowitz et al. initiated extensive research into diabetic gastroparesis.
- Understanding of pathophysiology, natural history, prognosis, and management has evolved significantly.
Observation:
- Gastric emptying is disordered in diabetic patients.
- The rate of gastric emptying significantly influences blood glucose control.
Findings:
- Over 25 years, knowledge has advanced regarding normal and abnormal gastric emptying in diabetes.
- The interplay between gastric emptying rate and glycemic regulation is a key focus.
Implications:
- Improved understanding aids in diagnosing and managing diabetic gastroparesis.
- Targeting gastric emptying may offer new strategies for glycemic control in diabetes.
- Further research is warranted to refine therapeutic approaches for diabetic gastroparesis.
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