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Updated: Aug 14, 2026

Inducing Apical Periodontitis in Mice
Published on: August 6, 2019
[Clinical and ultrastructural observations of juvenile periodontitis]
1Oral Hospital, Xi'an Medical University.
Abstract:
In this study, clinical data of 7 cases of juvenile periodontitis were analyzed in company with electron microscopic observations. It consisted of 6 females, and 1 male, aged from 12 to 18 years old. TEM showed chronic inflammation of the pocket walls, marked plasma cell and lymphocyte infiltration. Plasma cells revealed abundant dilated rough endoplasmic reticulum and were classified into three types. Numerous bacteria were found in lamina propria in one case, without any signs of phagocytosis. The collagen fibers were fragmented, dissolved and arranged out of order. The characteristics of clinical history, and the ultrastructural changes of the periodontal pocket were analyzed and discussed.

