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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

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Related Experiment Video

Updated: Jun 5, 2026

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
07:57

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

Published on: December 5, 2025

Skin grafts and local flaps.

Geoffrey G Hallock1, Steven F Morris

  • 1Bethlehem and Allentown, Pa.; and Halifax, Nova Scotia, Canada From the Division of Plastic Surgery, St. Luke's Hospital; Sacred Heart Hospital; Lehigh Valley Hospital; and the Departments of Surgery and Anatomy, Dalhousie University.

Plastic and Reconstructive Surgery
|January 5, 2011
PubMed
Summary

Expedited skin wound healing relies on skin grafts and local flaps when primary closure isn't possible. This article details their indications, techniques, and limitations for surgeons.

Related Experiment Videos

Last Updated: Jun 5, 2026

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
07:57

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

Published on: December 5, 2025

Area of Science:

  • Plastic Surgery
  • Wound Healing
  • Reconstructive Surgery

Background:

  • Expedited healing of skin wounds is crucial across surgical specialties.
  • Skin deficiencies necessitate alternative reconstructive methods.
  • Autogenous skin grafts and local flaps are primary solutions for wound coverage.

Purpose of the Study:

  • To differentiate between skin grafts and local flaps based on vascularization.
  • To outline indications, surgical anatomy, harvest techniques, and limitations of each method.
  • To present the "top ten" local workhorse flaps for reconstructive purposes.

Main Methods:

  • Review and differentiation of skin graft types and local flaps.
  • Description of surgical anatomy and harvest techniques for grafts and flaps.
  • Inclusion of accompanying videos for enhanced surgical technique visualization.

Main Results:

  • Skin grafts offer the simplest method for restoring skin integrity.
  • Local flaps are essential when skin grafts are contraindicated.
  • The article highlights key local flaps and their applications.

Conclusions:

  • Skin grafts and local flaps are fundamental for wound healing when primary or secondary intent is not feasible.
  • Knowledge of these techniques is vital for both reconstructive and aesthetic plastic surgeons.
  • Mastery ensures competency in managing surgical wounds effectively.