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Updated: Jun 5, 2026

Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay
Published on: April 28, 2022
The modified Patient and Observer Scar Assessment Scale: a novel approach to defining pathologic and nonpathologic
Regina M Fearmonti1, Jennifer E Bond, Detlev Erdmann
1Durham, N.C.; and Philadelphia, Pa. From the Division of Plastic, Reconstructive, Maxillofacial, and Oral Surgery, Department of Surgery, and Department of Pathology, Duke University Medical Center, and the Department of Orthopedics, University of Pennsylvania School of Medicine.
Background:
Scarring is a highly prevalent and multifactorial process, yet no studies to date have attempted to distinguish pathologic from nonpathologic scarring.
Methods:
This article defines and proposes methods of classifying pathologic scarring as it pertains to clinical presentation.
Results:
The authors propose a new scar scale that incorporates pain and functional impairment.
Conclusions:
The modified Patient and Observer Scar Assessment Scale is the first of its kind to factor in the functional deficits pain and pruritus of scarring into measurements of associated morbidity. This scale has great potential in evaluating patient response to treatment and analyzing clinical outcomes.
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